• Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency 

      Utheim, Tor Paaske; Utheim, Øygunn Aass; Khan, Qalbi; Sehic, Amer (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-01)
      The cornea is critical for normal vision as it allows allowing light transmission to the retina. The corneal epithelium is renewed by limbal epithelial cells (LEC), which are located in the periphery of the cornea, the limbus. Damage or disease involving LEC may lead to various clinical presentations of limbal stem cell deficiency (LSCD). Both severe pain and blindness may result. Transplantation ...
    • Effects of antibiotics on the developing enamel in neonatal mice 

      Schmalfuss, Andreas Jörn; Sehic, Amer; Brusevold, Ingvild Johnsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-29)
      Purpose Identifying factors causing Molar-Incisor Hypomineralization (MIH) is an ongoing challenge. Preterm infants, routinely treated with antibiotics in cases of suspected sepsis, are more commonly afected by dental developmental defects. This study aimed to investigate the efects of gentamycin and ampicillin on the developing enamel in neonatal CD-1 mice in vivo.<p> <p>Methods Neonatal mice ...
    • Five-minute Apgar score ≤ 5 and molar incisor hypomineralisation (MIH) - a case control study 

      Sidaly, Rivan; Schmalfuss, Andreas Jørn; Skaare, Anne B; Sehic, Amer; Stiris, Tom; Espelid, Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-22)
      Background: The aetiology of molar incisor hypomineralisation (MIH) is unclear. The asymmetric distribution of MIH in the dentition may indicate that an insult of short duration that affects ameloblasts at a vulnerable stage could be a causative factor. Apgar ≤ 5 at 5 min may indicate asphyxia (hypoxic-ischemic insult) during birth. It was hypnotised that low Apgar score during birth may cause MIH. ...
    • Genetic Aspects of Dental Erosive Wear and Dental Caries 

      Tulek, Amela; Mulic, Aida; Runningen, Maria; Lillemo, Jannike; Utheim, Tor Paaske; Khan, Qalbi; Sehic, Amer (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-13)
      Objectives. &e present review aims to give an overview of the literature focusing on novel genetic aspects of dental erosion and dental caries. Once the tooth erupts into the oral cavity, the regenerative capability of enamel is fundamentally limited due to the loss of dental epithelium during eruption. &e susceptibility or resistance to dental erosion and caries is presumably a result of environmental, ...